Neighbor-Joining Revealed - LIRMM - Laboratoire d’Informatique, de Robotique et de Microélectronique de Montpellier Accéder directement au contenu
Article Dans Une Revue Molecular Biology and Evolution Année : 2006

Neighbor-Joining Revealed

Résumé

It is nearly 20 years since the landmark paper (Saitou and Nei, 1987) in MBE introducing Neighbor-Joining (NJ). The method has become the most widely-used method for building phylogenetic trees from distances, and the original paper has been cited about 13,000 times (Science Citation Index ). Yet the question 'what does the NJ method seek to do?' has until recently proved somewhat elusive, leading to some imprecise claims and misunderstanding. However a rigorous answer to this question has recently been provided by further mathematical investigation, and the purpose of this note is to highlight these results and their significance for interpreting NJ. The origins of this story lie in a paper by Pauplin (2000) though its continuation has unfolded in more mathematically-inclined literature. Our aim here is to make these findings more widely accessible.
Fichier principal
Vignette du fichier
GascuelSteel_MBE06.pdf (76.2 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

lirmm-00136653 , version 1 (05-09-2012)

Identifiants

Citer

Olivier Gascuel, Mike Steel. Neighbor-Joining Revealed. Molecular Biology and Evolution, 2006, 23 (11), pp.1997-2000. ⟨10.1093/molbev/msl072⟩. ⟨lirmm-00136653⟩
188 Consultations
1419 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More