A measure of cortico-cortical potentials evoked by 10Hz direct electrical stimulation of the brain and by means of a differential recording mode of electrocorticographic signals

Abstract : Direct electrical stimulation (DES) at 60 Hz is used to perform real-time functional mapping of the brain during wide-awake neurosurgery. The electrophysiological effects of DES are largely unknown, locally and at a more remote distance. Here, by lowering the DES frequency to 10 Hz and by using a differential recording mode of electro-corticographic (ECoG) signals to improve the focality, we were able to record cortico-cortical evoked potentials easily with standard current amplitude of stimulation (2 mA). DES applied at 10 Hz and differential recording of ECoG could be used to map on-line the connectivity between different sub-cortical and cortical areas with a higher spatial accuracy.
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EMBC: Engineering in Medicine and Biology Conference, Aug 2016, Orlando, FL, United States. 38th IEEE Annual International Conference of the Engineering in Medicine and Biology Society, pp.4543-4546, 2016, 〈http://embc.embs.org/2016/〉. 〈10.1109/EMBC.2016.7591738〉
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François Bonnetblanc, Marion Vincent, Olivier Rossel, David Guiraud, Hugues Duffau. A measure of cortico-cortical potentials evoked by 10Hz direct electrical stimulation of the brain and by means of a differential recording mode of electrocorticographic signals. EMBC: Engineering in Medicine and Biology Conference, Aug 2016, Orlando, FL, United States. 38th IEEE Annual International Conference of the Engineering in Medicine and Biology Society, pp.4543-4546, 2016, 〈http://embc.embs.org/2016/〉. 〈10.1109/EMBC.2016.7591738〉. 〈lirmm-01391953〉

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