Given a graph G and a digraph D whose vertices are the edges of G, we investigate the problem of finding a spanning tree of G that satisfies the constraints imposed by D. The restrictions to add an edge in the tree depend on its neighborhood in D. Here, we generalize previously investigated problems by also considering as input functions ℓ and u on E(G) that give a lower and an upper bound, respectively, on the number of constraints that must be satisfied by each edge. The produced feasibility problem is denoted by G-DCST, while the optimization problem is denoted by G-DCMST. We show that G-DCST is NP-complete even under strong assumptions on the structures of G and D, as well as on functions ℓ and u. On the positive side, we prove two polynomial results, one for G-DCST and another for G-DCMST, and also give a simple exponentialtime algorithm along with a proof that it is asymptotically optimal under the ETH. Finally, we prove that other previously studied constrained spanning tree (CST) problems can be modeled within our framework, namely, the Conflict CST, the Forcing CST, the At Least One/All Dependency CST, the Maximum Degree CST, the Minimum Degree CST, and the Fixed-Leaves Minimum Degree CST.