The human operator largely relies on the perception of remote environmental conditions to make timely and correct decisions in a prescribed task when the robot is teleoperated in a remote place. However, due to the unknown and dynamic working environments, the manipulator’s performance and efficiency of the human-robot interaction in the tasks may degrade significantly. In this study, a novel method of human-centric interaction, through a physiological interface was presented to capture the information details of the remote operation environments. Simultaneously, in order to relieve workload of the human operator and to improve efficiency of the teleoperation system, an updated regression method was proposed to build up a nonlinear model of demonstration for the prescribed task. Considering that the demonstration data were of various lengths, dynamic time warping algorithm was employed first to synchronize the data over time before proceeding with other steps. The novelty of this method lies in the fact that both the task-specific information and the muscle parameters from the human operator have been taken into account in a single task; therefore, a more natural and safer interaction between the human and the robot could be achieved. The feasibility of the proposed method was demonstrated by experimental results.