This volume contains a selection of fully revised papers from the 37th Conference on Data Management – Principles, Technologies and Applications (BDA 2021). For this special issue, we have selected five articles covering a wide range of timely data management research topics on threats modeling, RDF schema generation, data coverage optimization, data quality, storage on synthetic DNA, and data science. All authors were invited to prepare and submit journal versions of their contributions which have been fully re-reviewed by the editorial board of this special issue. One of the papers in this special issue is an extended version of an international conference paper published in ISWC 2021. We would like to take this opportunity to express our sincere thanks to all authors and the editorial board of this special issue for their effort and their valuable contribution in raising the quality of the camera-ready version of the papers. Finally, we are grateful to the Editors-in-Chief, Abdelkader Hameurlain and A Min Tjoa, for giving us the opportunity to publish this special issue as part of TLDKS Journal series.