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Automatic Generation of Noise-Free Time-Activity Curve with Gated Blood-Pool Emission Tomography Using Deformation of a Reference Curve

Abstract : This paper describes a new method for assessing clinical parameters from a noisy regional time-activity curve (TAC) in tomographic gated blood-pool ventriculography. This method is based on a priori knowledge on the shape of a TAC, and shape approximation. The rejection method was used to generate different random Poisson deviates, covering standard count levels, of six representative TACs in order to test and compare the proposed method with harmonic and multiharmonic reconstruction methods. These methods were compared by evaluating four clinical parameters: time of end systole, amplitude, peak ejection and filling rates. Overall, the accuracy of assessment of these parameters was found to be better with the method described in this paper than with standard multiharmonic fits.
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https://hal-lirmm.ccsd.cnrs.fr/lirmm-00108539
Contributor : Christine Carvalho de Matos <>
Submitted on : Monday, October 23, 2006 - 7:42:46 AM
Last modification on : Friday, May 15, 2020 - 12:22:04 PM
Long-term archiving on: : Tuesday, April 6, 2010 - 8:26:34 PM

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Charles Caderas de Kerleau, Jean-François Crouzet, Ehoud Ahronovitz, Michel Rossi, Denis Mariano-Goulart. Automatic Generation of Noise-Free Time-Activity Curve with Gated Blood-Pool Emission Tomography Using Deformation of a Reference Curve. IEEE Transactions on Medical Imaging, Institute of Electrical and Electronics Engineers, 2004, 23 (4), pp.485-491. ⟨10.1109/TMI.2004.825638⟩. ⟨lirmm-00108539⟩

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