Automatic Generation of Noise-Free Time-Activity Curve with Gated Blood-Pool Emission Tomography Using Deformation of a Reference Curve - LIRMM - Laboratoire d’Informatique, de Robotique et de Microélectronique de Montpellier Access content directly
Journal Articles IEEE Transactions on Medical Imaging Year : 2004

Automatic Generation of Noise-Free Time-Activity Curve with Gated Blood-Pool Emission Tomography Using Deformation of a Reference Curve

Abstract

This paper describes a new method for assessing clinical parameters from a noisy regional time-activity curve (TAC) in tomographic gated blood-pool ventriculography. This method is based on a priori knowledge on the shape of a TAC, and shape approximation. The rejection method was used to generate different random Poisson deviates, covering standard count levels, of six representative TACs in order to test and compare the proposed method with harmonic and multiharmonic reconstruction methods. These methods were compared by evaluating four clinical parameters: time of end systole, amplitude, peak ejection and filling rates. Overall, the accuracy of assessment of these parameters was found to be better with the method described in this paper than with standard multiharmonic fits.
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Dates and versions

lirmm-00108539 , version 1 (23-10-2006)

Identifiers

Cite

Charles Caderas de Kerleau, Jean-François Crouzet, Ehoud Ahronovitz, Michel Rossi, Denis Mariano-Goulart. Automatic Generation of Noise-Free Time-Activity Curve with Gated Blood-Pool Emission Tomography Using Deformation of a Reference Curve. IEEE Transactions on Medical Imaging, 2004, 23 (4), pp.485-491. ⟨10.1109/TMI.2004.825638⟩. ⟨lirmm-00108539⟩
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