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Conference Poster Year : 2010

A Computational Model of the Primary Auditory Neuron Activity

Abstract

Sound translation into neural message at the first auditory synapse is of prime importance for providing organism with sound environment. Here, we compiled experimental features of the primary auditory neurons into a computational model, composed of two distinct compartments (i.e., afferent bouton and axon). Simulation of the model closely reproduces the whole biophysical properties of both excitatory post-synaptic currents and action potentials firing. This simple model provides a powerful tool to understand the synaptic disorders on the sound neural coding at the first auditory synapse.

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lirmm-00506095 , version 1 (27-07-2010)

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Christophe Michel, Régis Nouvian, Christine Azevedo Coste, Jean-Luc Puel, Jérôme Bourien. A Computational Model of the Primary Auditory Neuron Activity. EMBC: Engineering in Medicine and Biology Conference, Aug 2010, Buenos Aires, Argentina. 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp.722-725, 2010, ⟨10.1109/IEMBS.2010.5626273⟩. ⟨lirmm-00506095⟩
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