Stimulation of small diameter myelinated and unmyelinated abdominal vagal neurons using high frequency pulses

Charles-Henri Malbert 1 Jean Louis Divoux 2 Paweł Maciejasz 2, 3 Chloé Picq 2 David Andreu 3 David Guiraud 3
3 DEMAR - Artificial movement and gait restoration
LIRMM - Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier, CRISAM - Inria Sophia Antipolis - Méditerranée
Abstract : The voltage required to stimulate small diameter myelinated (Adelta fibres) and unmyelinated (C fibres) neurons consistently is so large that it is unsafe for chronic vagal stimulation. We present here a solution that reduces by 80% the amount of electrical charge necessary to produce action potential. These solutions were tested in a porcine model that allowed simultaneously to locate the origin of the afferent neurons, to stimulate the vagal trunks at distance from the recording electrode and to record the evoked activity of one neuron using the single afferent method. The reduction in current supplied by the most effective pulse pattern makes possible to incorporate this solution in an implanted device without damaging the vagal nerve
Complete list of metadatas

https://hal-lirmm.ccsd.cnrs.fr/lirmm-01586137
Contributor : David Guiraud <>
Submitted on : Tuesday, September 12, 2017 - 2:56:01 PM
Last modification on : Monday, September 2, 2019 - 2:46:17 PM

Identifiers

Citation

Charles-Henri Malbert, Jean Louis Divoux, Paweł Maciejasz, Chloé Picq, David Andreu, et al.. Stimulation of small diameter myelinated and unmyelinated abdominal vagal neurons using high frequency pulses. NER: Neural Engineering, Apr 2015, Montpellier, France. pp.510-513, ⟨10.1109/NER.2015.7146671⟩. ⟨lirmm-01586137⟩

Share

Metrics

Record views

491