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Conference papers
Stimulation of small diameter myelinated and unmyelinated abdominal vagal neurons using high frequency pulses
Abstract : The voltage required to stimulate small diameter myelinated (Adelta fibres) and unmyelinated (C fibres) neurons consistently is so large that it is unsafe for chronic vagal stimulation. We present here a solution that reduces by 80% the amount of electrical charge necessary to produce action potential. These solutions were tested in a porcine model that allowed simultaneously to locate the origin of the afferent neurons, to stimulate the vagal trunks at distance from the recording electrode and to record the evoked activity of one neuron using the single afferent method. The reduction in current supplied by the most effective pulse pattern makes possible to incorporate this solution in an implanted device without damaging the vagal nerve
Keywords :
action potential
chronic vagal stimulation
C fibres
Stomach
electrical charge
evoked activity
high frequency pulses
implanted device
porcine model
single afferent method
recording electrode
pulse pattern
small diameter myelinated abdominal vagal neuron stimulation
neurophysiology
biomedical electrodes
bioelectric potentials
Adelta fibres
Software
unmyelinated abdominal vagal neuron stimulation
vagal trunks
Animals
Electric potential
Electrodes
Neurons
Shape
https://hal-lirmm.ccsd.cnrs.fr/lirmm-01586137
Contributor : David Guiraud <>
Submitted on : Tuesday, September 12, 2017 - 2:56:01 PM
Last modification on : Tuesday, March 23, 2021 - 3:31:10 AM
Contributor : David Guiraud <>
Submitted on : Tuesday, September 12, 2017 - 2:56:01 PM
Last modification on : Tuesday, March 23, 2021 - 3:31:10 AM